If you experience frequent crashes and you are using Vista, try this to fix it:
Change your "Texture Details" and the "Effects Fidelity" to medium and see if it helps solving the problem.
This is a temporarily fix, Relic is aware of the problem and working on it!
Update on 23rd of february:
Improved memory heap management to reduce 'out-of-memory' crashes that were plaguing certain systems, including 32-Bit Vista on High and Ultra settings. Often reported as 'error 183 failed to create to create dump'